{
  description = "Python flake with native packages";

  inputs.nixpkgs.url = "github:NixOS/nixpkgs/nixos-unstable";
  inputs.flake-utils.url = "github:numtide/flake-utils";

  outputs = { self, nixpkgs, flake-utils}:
  flake-utils.lib.eachDefaultSystem (system:
  let
    pkgs = import nixpkgs {
      inherit system;
      config.allowUnfree = true;
    };
  in {
    devShells.default = pkgs.mkShell {
      packages = with pkgs; [
        python312
        python312Packages.biopython # Bio-informatics

        # Editor of your choice
        # jetbrains.pycharm-professional
      ];
    };
  });
}